5QXI

PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with PC587

5QXI の概要

• エントリーDOI: 10.2210/pdb5qxi/pdb
• Group deposition: PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening (G_1002118)
• 分子名称: ATPase family AAA domain-containing protein 2, (4R,4aS,7aS,9S)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3',4':5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol, (4R,4aR,7aS,9R)-3,10-dimethyl-5,6,7,7a,8,9-hexahydro-4H-4a,9-epiminopyrrolo[3',4':5,6]cyclohepta[1,2-d][1,2]oxazol-4-ol, ... (6 entities in total)
• 機能のキーワード: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16299.39

構造登録者

Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F. (登録日: 2020-02-11, 公開日: 2020-04-08, 最終更新日: 2024-03-06)

• 主引用文献: Snee, M.,Talon, R.,Fowley, D.,Collins, P.,Nelson, A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Von-Delft, F.; PanDDA analysis group deposition - Bromodomain of human ATAD2 fragment screening; To Be Published,

実験手法

X-RAY DIFFRACTION (1.64 Å)