5QRN

PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z54226006

Summary for 5QRN

Group depositionPanDDA analysis group deposition (G_1002080)
DescriptorT-box transcription factor T, CADMIUM ION, (2,6-difluorophenyl)(pyrrolidin-1-yl)methanone, ... (4 entities in total)
Functional Keywordssgc - diamond i04-1 fragment screening, pandda, xchemexplorer, transcription
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight20370.85
Authors
Newman, J.A.,Gavard, A.E.,Fernandez-Cid, A.,Sherestha, L.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2019-05-25, release date: 2019-07-10, Last modification date: 2019-08-07)
Primary citation
Newman, J.A.,Gavard, A.E.,Fernandez-Cid, A.,Sherestha, L.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O.
PanDDA analysis group deposition
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.62 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2645 1.2% 6.0% 7.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution