5QQR

PanDDA analysis group deposition -- Crystal Structure of human ALAS2A in complex with Z1171217421

Summary for 5QQR

• Entry DOI: 10.2210/pdb5qqr/pdb
• Group deposition: PanDDA analysis group deposition (G_1002078)
• Descriptor: 5-aminolevulinate synthase, erythroid-specific, mitochondrial, PYRIDOXAL-5'-PHOSPHATE, 1-[(2-methyl-1,3-thiazol-5-yl)methyl]piperazine, ... (4 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, pandda, xchemexplorer, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 105192.69

Authors

Bezerra, G.A.,Foster, W.,Bailey, H.,Shrestha, L.,Krojer, T.,Talon, R.,Brandao-Neto, J.,Douangamath, A.,Nicola, B.B.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Brennan, P.E.,Yue, W.W. (deposition date: 2019-05-22, release date: 2019-08-07, Last modification date: 2024-03-06)

• Primary citation: Bezerra, G.A.,Foster, W.,Bailey, H.,Shrestha, L.,Krojer, T.,Talon, R.,Brandao-Neto, J.,Douangamath, A.,Nicola, B.B.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Brennan, P.E.,Yue, W.W.; PanDDA analysis group deposition; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.46 Å)