5PAQ
Crystal Structure of Factor VIIa in complex with 2-[(1-aminoisoquinolin-6-yl)amino]-2-(3-ethoxy-4-propan-2-yloxyphenyl)-1-(2-phenylpyrrolidin-1-yl)ethanone
Summary for 5PAQ
Entry DOI | 10.2210/pdb5paq/pdb |
Group deposition | Crystal Structures of Factor VIIa Complexes (G_1002015) |
Descriptor | Coagulation factor VII light chain, Coagulation factor VII heavy chain, CHLORIDE ION, ... (8 entities in total) |
Functional Keywords | glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: P08709 P08709 |
Total number of polymer chains | 2 |
Total formula weight | 36039.51 |
Authors | Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (deposition date: 2016-11-10, release date: 2017-06-21, Last modification date: 2024-04-03) |
Primary citation | Mayweg, A.,Roever, S.,Rudolph, M.G. Crystal Structure of a Factor VIIa complex To be published, |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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