5PA0
humanized rat COMT in complex with 3-hydroxy-1-methyl-5-phenylpyridin-2-one
Summary for 5PA0
Entry DOI | 10.2210/pdb5pa0/pdb |
Group deposition | Crystal Structure of COMT complex (G_1002014) |
Descriptor | Catechol O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 1-methyl-3-oxidanyl-5-phenyl-pyridin-2-one, ... (8 entities in total) |
Functional Keywords | methyltransferase, neurotransmitter degradation, transferase |
Biological source | Rattus norvegicus (Rat) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
Total number of polymer chains | 1 |
Total formula weight | 26307.86 |
Authors | Ehler, A.,Lerner, C.,Rudolph, M.G. (deposition date: 2016-10-19, release date: 2017-11-22, Last modification date: 2024-04-03) |
Primary citation | Lerner, C.,Jakob-Roetne, R.,Groebke-Zbinden, K.,Buettelmann, B.,Rudolph, M.G. Crystal Structure of a COMT complex To be published, |
Experimental method |
Structure validation
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