5P8W

Crystal Structure of COMT in complex with [5-(2,4-dimethyl-1,3-thiazol-5-yl)-1H-pyrazol-3-yl]methanamine

5P8W の概要

• エントリーDOI: 10.2210/pdb5p8w/pdb
• Group deposition: Crystal Structure of COMT complex (G_1002007)
• 分子名称: Catechol O-methyltransferase, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, [5-(2,4-dimethyl-1,3-thiazol-5-yl)-1H-pyrazol-3-yl]methanamine, ... (6 entities in total)
• 機能のキーワード: methyltransferase, neurotransmitter degradation, transferase
• 由来する生物種: Rattus norvegicus (Rat)
• 細胞内の位置: Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 75423.62

構造登録者

Ehler, A.,Lerner, C.,Rudolph, M.G. (登録日: 2016-08-25, 公開日: 2016-09-07, 最終更新日: 2024-05-01)

• 主引用文献: Lerner, C.,Rudolph, M.G.; Crystal Structure of COMT complex; To be published,

実験手法

X-RAY DIFFRACTION (2.03 Å)