5OWQ
Human STK10 bound to dovitinib
Summary for 5OWQ
Entry DOI | 10.2210/pdb5owq/pdb |
Descriptor | Serine/threonine-protein kinase 10, 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one (2 entities in total) |
Functional Keywords | kinase, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane ; Peripheral membrane protein : O94804 |
Total number of polymer chains | 2 |
Total formula weight | 69382.07 |
Authors | Szklarz, M.,von Delft, F.,Bountra, C.,Knapp, S.,Edwards, A.M.,Arrowsmith, C.,Elkins, J.M. (deposition date: 2017-09-04, release date: 2017-09-13, Last modification date: 2024-05-01) |
Primary citation | Elkins, J.M. Human STK10 bound to dovitinib To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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