5OUG

Humanized alpha-AChBP (acetylcholine binding protein) in complex with lobeline and allosteric binder fragment 4.

5OUG の概要

• エントリーDOI: 10.2210/pdb5oug/pdb
• 関連するPDBエントリー: 5afm
• 分子名称: Humanized alpha-AChBP, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: acetylcholine binding protein, nicotinic acetylcholine receptor, choline-binding protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 127198.39

構造登録者

Delbart, F.,Gruss, F.,Ulens, C. (登録日: 2017-08-23, 公開日: 2017-12-20, 最終更新日: 2020-07-29)

• 主引用文献: Delbart, F.,Brams, M.,Gruss, F.,Noppen, S.,Peigneur, S.,Boland, S.,Chaltin, P.,Brandao-Neto, J.,von Delft, F.,Touw, W.G.,Joosten, R.P.,Liekens, S.,Tytgat, J.,Ulens, C.; An allosteric binding site of the alpha 7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein.; J. Biol. Chem., 293:2534-2545, 2018; PubMed: 29237730; DOI: 10.1074/jbc.M117.815316

実験手法

X-RAY DIFFRACTION (2.57 Å)