5OTV
Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cyc/Thr11Hcs
Summary for 5OTV
Entry DOI | 10.2210/pdb5otv/pdb |
Descriptor | Glucagon-like peptide 1 receptor, Glucagon (3 entities in total) |
Functional Keywords | glucagon-like peptide 1, gpcr, cyclic peptides, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 33911.44 |
Authors | Mortensen, S. (deposition date: 2017-08-22, release date: 2018-07-04, Last modification date: 2024-03-06) |
Primary citation | Oddo, A.,Mortensen, S.,Thogersen, H.,De Maria, L.,Hennen, S.,McGuire, J.N.,Kofoed, J.,Linderoth, L.,Reedtz-Runge, S. alpha-Helix or beta-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4. Biochemistry, 57:4148-4154, 2018 Cited by PubMed: 29877701DOI: 10.1021/acs.biochem.8b00105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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