5OT3
Crystal Structure of the Protein-Kinase A catalytic subunit from Criteculus Griseus in complex with compounds RKp191 and RKp117
5OT3 の概要
エントリーDOI | 10.2210/pdb5ot3/pdb |
分子名称 | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor, [2-[(4-isoquinolin-5-ylsulfonyl-1,4-diazepan-1-yl)methyl]phenyl]boronic acid, ... (7 entities in total) |
機能のキーワード | complex, peptidic ligand, transferase |
由来する生物種 | Cricetulus griseus (Chinese hamster) 詳細 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 43911.99 |
構造登録者 | |
主引用文献 | Mueller, J.M.,Kirschner, R.,Geyer, A.,Klebe, G. Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019 Cited by DOI: 10.1021/acsomega.8b02364主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.04 Å) |
構造検証レポート
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