5OQI

Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C E63A mutant, beta-2microglobulin, and ovalbumin-derived peptide

5OQI の概要

• エントリーDOI: 10.2210/pdb5oqi/pdb
• 分子名称: Beta-2-microglobulin,H-2 class I histocompatibility antigen, K-B alpha chain (2 entities in total)
• 機能のキーワード: diagnosis, epitopes, major histocompatibility complex, mice, models, molecular, molecular conformation, peptides, receptors, antigen, t-cell, t-lymphocytes, vaccines, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 96247.15

構造登録者

Mikolajek, H.,Werner, J.M.,Beton, M.E. (登録日: 2017-08-11, 公開日: 2018-04-11, 最終更新日: 2024-01-17)

• 主引用文献: Papakyriakou, A.,Reeves, E.,Beton, M.,Mikolajek, H.,Douglas, L.,Cooper, G.,Elliott, T.,Werner, J.M.,James, E.; The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1.; J. Biol. Chem., 293:7538-7548, 2018; PubMed: 29599287; DOI: 10.1074/jbc.RA117.000313

実験手法

X-RAY DIFFRACTION (2.4 Å)