5OPL
Crystal structure of K25E cN-II mutant
Summary for 5OPL
Entry DOI | 10.2210/pdb5opl/pdb |
Related | 5opl |
Descriptor | Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | nucleotidase, relapsed leukemia, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 64942.02 |
Authors | Kugler, M.,Hnizda, A.,Pachl, P.,Rezacova, P. (deposition date: 2017-08-10, release date: 2018-06-13, Last modification date: 2024-05-08) |
Primary citation | Hnizda, A.,Fabry, M.,Moriyama, T.,Pachl, P.,Kugler, M.,Brinsa, V.,Ascher, D.B.,Carroll, W.L.,Novak, P.,Zaliova, M.,Trka, J.,Rezacova, P.,Yang, J.J.,Veverka, V. Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation. Leukemia, 32:1393-1403, 2018 Cited by PubMed: 29535428DOI: 10.1038/s41375-018-0073-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)