5OPH
G-quadruplex structure of DNA oligonucleotide containing GGGGCC repeats linked to ALS and FTD
Summary for 5OPH
Entry DOI | 10.2210/pdb5oph/pdb |
NMR Information | BMRB: 34168 |
Descriptor | DNA (5'-D(*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*CP*GP*GP*(BGM)P*G)-3') (1 entity in total) |
Functional Keywords | g-quadruplex, dna, nucelar magnetic resonance, k+ solution, antiparallel, four g-quartets, edgewise loops, stacking, ggggcc-repat, als and ftd, neurodegenerative disorders, repetitive sequences, nucleic acid, 8br-dg, modified residue |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 7036.32 |
Authors | Brcic, J.,Plavec, J. (deposition date: 2017-08-09, release date: 2018-08-29, Last modification date: 2024-05-15) |
Primary citation | Brcic, J.,Plavec, J. NMR structure of a G-quadruplex formed by four d(G4C2) repeats: insights into structural polymorphism. Nucleic Acids Res., 46:11605-11617, 2018 Cited by PubMed: 30277522DOI: 10.1093/nar/gky886 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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