5OOC
Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP
Summary for 5OOC
Entry DOI | 10.2210/pdb5ooc/pdb |
Related | 5ONV 5OOD 5OOE 5OOF 6T1Y 6T20 6T23 6T24 6T25 |
EMDB information | 10363 10364 10365 10366 10367 3835 3836 3837 3838 3839 |
Descriptor | Actin, alpha skeletal muscle, ADENOSINE-5'-DIPHOSPHATE, (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ... (4 entities in total) |
Functional Keywords | cytoskeleton, nucleotide states, filament stability, cell migration, structural protein |
Biological source | Oryctolagus cuniculus (Rabbit) |
Total number of polymer chains | 5 |
Total formula weight | 215004.90 |
Authors | Merino, F.,Pospich, S.,Funk, J.,Kuellmer, F.,Arndt, H.-D.,Bieling, P.,Raunser, S. (deposition date: 2017-08-07, release date: 2018-06-13, Last modification date: 2019-10-16) |
Primary citation | Merino, F.,Pospich, S.,Funk, J.,Wagner, T.,Kullmer, F.,Arndt, H.D.,Bieling, P.,Raunser, S. Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM. Nat. Struct. Mol. Biol., 25:528-537, 2018 Cited by PubMed: 29867215DOI: 10.1038/s41594-018-0074-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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