5OMC

Crystal structure of K. lactis Ddc2 N-terminus in complex with S. cerevisiae Rfa1 (K45E mutant) N-OB domain

5OMC の概要

• エントリーDOI: 10.2210/pdb5omc/pdb
• 分子名称: Replication factor A protein 1, DNA damage checkpoint protein LCD1, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: oligonucleotide-binding fold, coiled-coil domain, complex, mutant, protein binding
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• 細胞内の位置: Nucleus: P22336; Cytoplasm : Q6CUV9
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 56764.37

構造登録者

Deshpande, I.,Seeber, A.,Shimada, K.,Keusch, J.J.,Gut, H.,Gasser, S.M. (登録日: 2017-07-28, 公開日: 2017-10-25, 最終更新日: 2024-01-17)

• 主引用文献: Deshpande, I.,Seeber, A.,Shimada, K.,Keusch, J.J.,Gut, H.,Gasser, S.M.; Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.; Mol. Cell, 68:431-445.e5, 2017; PubMed: 29033322; DOI: 10.1016/j.molcel.2017.09.019

実験手法

X-RAY DIFFRACTION (2.38 Å)