5OHB
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Piperidin-2-one (Valerolactam)
Summary for 5OHB
| Entry DOI | 10.2210/pdb5ohb/pdb |
| Descriptor | Cereblon isoform 4, ZINC ION, piperidin-2-one, ... (4 entities in total) |
| Functional Keywords | teratogenicity, protein degradation, substrate recognition, ubiquitin ligase, unknown function |
| Biological source | Magnetospirillum gryphiswaldense MSR-1 |
| Total number of polymer chains | 3 |
| Total formula weight | 41604.35 |
| Authors | Boichenko, I.,Albrecht, R.,Lupas, A.N.,Hernandez Alvarez, B.,Hartmann, M.D. (deposition date: 2017-07-14, release date: 2018-10-10, Last modification date: 2024-01-17) |
| Primary citation | Boichenko, I.,Bar, K.,Deiss, S.,Heim, C.,Albrecht, R.,Lupas, A.N.,Hernandez Alvarez, B.,Hartmann, M.D. Chemical Ligand Space of Cereblon. Acs Omega, 3:11163-11171, 2018 Cited by PubMed: 31459225DOI: 10.1021/acsomega.8b00959 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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