5OG9

The BM3 mutant WIFI-WC heme domain in complex with testosterone

5OG9 の概要

• エントリーDOI: 10.2210/pdb5og9/pdb
• 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ... (6 entities in total)
• 機能のキーワード: cytochrome p450, testosterone, laboratory evolution, hydroxylation, steroids, oxidoreductase
• 由来する生物種: Bacillus megaterium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 110817.23

構造登録者

Gamble, C.,Munro, A.W.,Leys, D. (登録日: 2017-07-12, 公開日: 2018-08-01, 最終更新日: 2024-01-17)

• 主引用文献: Acevedo-Rocha, C.G.,Gamble, C.,Lonsdale, R.,Li, A.,Nett, N.,Hoebenreich, S.,Lingnau, J.,Wirtz, C.,Fares, C.,Hinrichs, H.,Deege, A.,Mulholland, A.J.,Nov, Y.,Leys, D.,Munro, A.W.,Reetz, M.T.; Regio- and diastereoselective hydroxylation of steroids using P450-BM3: Readdressing the numbers problem in directed evolution; To Be Published,

実験手法

X-RAY DIFFRACTION (2.09 Å)