5OE7

Structure of OTULIN bound to the Met1-linked diubiquitin activity probe

Summary for 5OE7

DescriptorUbiquitin thioesterase otulin, Polyubiquitin-C (2 entities in total)
Functional Keywordsdeubiquitinase complex otu, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm  Q96BN8
Ubiquitin: Cytoplasm  P0CG48
Total number of polymer chains2
Total molecular weight48219.28
Authors
Elliott, P.R.,Komander, D. (deposition date: 2017-07-07, release date: 2017-09-27, Last modification date: 2017-11-01)
Primary citation
Weber, A.,Elliott, P.R.,Pinto-Fernandez, A.,Bonham, S.,Kessler, B.M.,Komander, D.,El Oualid, F.,Krappmann, D.
A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Cell Chem Biol, 24:1299-1313.e7, 2017
PubMed: 28919039 (PDB entries with the same primary citation)
DOI: 10.1016/j.chembiol.2017.08.006
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.300100017.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution