5OD1

Structure of the engineered metalloesterase MID1sc10 complexed with a phosphonate transition state analogue

5OD1 の概要

• エントリーDOI: 10.2210/pdb5od1/pdb
• 分子名称: MID1sc10, ZINC ION, [2-oxidanylidene-7-[oxidanyl-[(1~{S})-1-phenylethyl]phosphoryl]oxy-chromen-4-yl]methanesulfonic acid, ... (5 entities in total)
• 機能のキーワード: directed evolution, engineered metalloenzyme, de novo protein-hydrolase, de novo protein-hydrolase complex, de novo protein/hydrolase
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11450.94

構造登録者

Mittl, P.R.E.,Studer, S.,Hansen, D.A.,Hilvert, D. (登録日: 2017-07-04, 公開日: 2018-12-12, 最終更新日: 2020-04-22)

• 主引用文献: Studer, S.,Hansen, D.A.,Pianowski, Z.L.,Mittl, P.R.E.,Debon, A.,Guffy, S.L.,Der, B.S.,Kuhlman, B.,Hilvert, D.; Evolution of a highly active and enantiospecific metalloenzyme from short peptides.; Science, 362:1285-1288, 2018; PubMed: 30545884; DOI: 10.1126/science.aau3744

実験手法

X-RAY DIFFRACTION (1.34 Å)