5OBH
Crystal structure of glycine binding protein in complex with bicuculline
Summary for 5OBH
Entry DOI | 10.2210/pdb5obh/pdb |
Related PRD ID | PRD_900017 |
Descriptor | Soluble acetylcholine receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (5S)-6,6-dimethyl-5-[(6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl]-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium, ... (6 entities in total) |
Functional Keywords | receptor, acetylcholine binding, signaling protein |
Biological source | Aplysia californica (California sea hare) |
Total number of polymer chains | 5 |
Total formula weight | 144707.61 |
Authors | Dawson, A.,Hunter, W.N.,Jones, M. (deposition date: 2017-06-27, release date: 2018-08-01, Last modification date: 2024-01-17) |
Primary citation | Jones, M.J.,Dawson, A.,Hales, T.G.,Hunter, W.N. A Structural Rationale for N-Methylbicuculline Acting as a Promiscuous Competitive Antagonist of Inhibitory Pentameric Ligand-Gated Ion Channels. Chembiochem, 21:1526-1533, 2020 Cited by PubMed: 31859406DOI: 10.1002/cbic.201900680 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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