5O98

Binary complex of Catharanthus roseus Vitrosamine Synthase with NADP+

Summary for 5O98

• Entry DOI: 10.2210/pdb5o98/pdb
• Descriptor: Alcohol dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: alkaloid, natural product, biosynthesis, short chain dehydrogenase, oxidoreductase
• Biological source: Catharanthus roseus (Madagascar periwinkle)
• Total number of polymer chains: 2
• Total formula weight: 70509.21

Authors

Stavrinides, A.K.,Tatsis, E.C.,Dang, T.T.,Caputi, L.,Stevenson, C.E.M.,Lawson, D.M.,Schneider, B.,O'Connor, S.E. (deposition date: 2017-06-16, release date: 2018-02-21, Last modification date: 2024-01-17)

• Primary citation: Stavrinides, A.K.,Tatsis, E.C.,Dang, T.T.,Caputi, L.,Stevenson, C.E.M.,Lawson, D.M.,Schneider, B.,O'Connor, S.E.; Discovery of a Short-Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid.; Chembiochem, 19:940-948, 2018; PubMed: 29424954; DOI: 10.1002/cbic.201700621

Experimental method

X-RAY DIFFRACTION (1.55 Å)