5O84

Glutathione S-transferase Tau 23 (partially oxidized)

Summary for 5O84

Entry DOI	10.2210/pdb5o84/pdb
Related	6EP6 6EP7
Descriptor	Glutathione S-transferase U23, FORMIC ACID, 1,2-ETHANEDIOL, ... (7 entities in total)
Functional Keywords	glutathione s-transferase, tau, transferase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Cellular location	Cytoplasm, cytosol : Q9M9F1
Total number of polymer chains	1
Total formula weight	25802.77
Authors	Young, D.R.,Van Molle, I.,Tossounian, M.,Messens, J. (deposition date: 2017-06-12, release date: 2017-10-25, Last modification date: 2024-01-17)
Primary citation	Tossounian, M.A.,Van Molle, I.,Wahni, K.,Jacques, S.,Gevaert, K.,Van Breusegem, F.,Vertommen, D.,Young, D.,Rosado, L.A.,Messens, J. Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage. Biochim. Biophys. Acta, 1862:775-789, 2018 Cited by PubMed Abstract: Glutathione transferases play an important role as detoxifying enzymes. In A. thaliana, elevated levels of reactive oxygen species (ROS), provoked during biotic and abiotic stress, influence the activity of GSTU23. The aim of this study is to determine the impact of oxidative stress on the function and structure of GSTU23. PubMed: 29031766 DOI: 10.1016/j.bbagen.2017.10.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation