5O7W

Crystal structure of the 4-FLUORO RSL lectin in complex with Lewis x tetrasaccharide

5O7W の概要

• エントリーDOI: 10.2210/pdb5o7w/pdb
• 分子名称: Putative fucose-binding lectin protein, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-galactopyranose, ... (7 entities in total)
• 機能のキーワード: lectin, fluorinated tryptophan, lewis x, carbohydrate, sugar binding protein
• 由来する生物種: Ralstonia solanacearum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 21571.75

構造登録者

Varrot, A. (登録日: 2017-06-09, 公開日: 2018-06-06, 最終更新日: 2024-01-17)

• 主引用文献: Tobola, F.,Lelimousin, M.,Varrot, A.,Gillon, E.,Darnhofer, B.,Blixt, O.,Birner-Gruenberger, R.,Imberty, A.,Wiltschi, B.; Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs.; ACS Chem. Biol., 13:2211-2219, 2018; PubMed: 29812892; DOI: 10.1021/acschembio.8b00377

実験手法

X-RAY DIFFRACTION (1.35 Å)