5O6C

Crystal Structure of a threonine-selective RCR E3 ligase

Summary for 5O6C

• Entry DOI: 10.2210/pdb5o6c/pdb
• Descriptor: E3 ubiquitin-protein ligase MYCBP2, ZINC ION (3 entities in total)
• Functional Keywords: ring zinc binding threonine e3 ligase, ligase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : O75592
• Total number of polymer chains: 1
• Total formula weight: 30108.66

Authors

Pao, K.-C.,Rafie, K.Z.,van Aalten, D.,Virdee, S. (deposition date: 2017-06-06, release date: 2018-04-18, Last modification date: 2018-05-02)

• Primary citation: Pao, K.C.,Wood, N.T.,Knebel, A.,Rafie, K.,Stanley, M.,Mabbitt, P.D.,Sundaramoorthy, R.,Hofmann, K.,van Aalten, D.M.F.,Virdee, S.; Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.; Nature, 556:381-385, 2018; PubMed: 29643511; DOI: 10.1038/s41586-018-0026-1

Experimental method

X-RAY DIFFRACTION (1.75 Å)