5O6C
Crystal Structure of a threonine-selective RCR E3 ligase
Summary for 5O6C
Entry DOI | 10.2210/pdb5o6c/pdb |
Descriptor | E3 ubiquitin-protein ligase MYCBP2, ZINC ION (3 entities in total) |
Functional Keywords | ring zinc binding threonine e3 ligase, ligase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : O75592 |
Total number of polymer chains | 1 |
Total formula weight | 30108.66 |
Authors | Pao, K.-C.,Rafie, K.Z.,van Aalten, D.,Virdee, S. (deposition date: 2017-06-06, release date: 2018-04-18, Last modification date: 2024-05-08) |
Primary citation | Pao, K.C.,Wood, N.T.,Knebel, A.,Rafie, K.,Stanley, M.,Mabbitt, P.D.,Sundaramoorthy, R.,Hofmann, K.,van Aalten, D.M.F.,Virdee, S. Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity. Nature, 556:381-385, 2018 Cited by PubMed: 29643511DOI: 10.1038/s41586-018-0026-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report