5O50

Glycogen Phosphorylase b in complex with 33a

Summary for 5O50

Entry DOI	10.2210/pdb5o50/pdb
Descriptor	Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-phenyl-1~{H}-imidazol-2-yl)oxane-3,4-diol, ... (5 entities in total)
Functional Keywords	alpha and beta protein, transferase
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	98191.88
Authors	Kantsadi, A.L.,Kyriakis, E.,Stravodimos, G.A.,Solovou, T.G.A.,Chatzileontiadou, D.S.,Skamnaki, V.T.,Leonidas, D.D. (deposition date: 2017-05-31, release date: 2017-09-27, Last modification date: 2017-11-29)
Primary citation	Bokor, E.,Kyriakis, E.,Solovou, T.G.A.,Koppany, C.,Kantsadi, A.L.,Szabo, K.E.,Szakacs, A.,Stravodimos, G.A.,Docsa, T.,Skamnaki, V.T.,Zographos, S.E.,Gergely, P.,Leonidas, D.D.,Somsak, L. Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60:9251-9262, 2017 Cited by PubMed: 28925695 DOI: 10.1021/acs.jmedchem.7b01056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation