5O15
Crystal structure of bifunctional dehydratase-cyclase domain in ambruticin biosynthesis
Summary for 5O15
Entry DOI | 10.2210/pdb5o15/pdb |
Descriptor | AmbC, GLYCEROL (3 entities in total) |
Functional Keywords | biocatalysis, cyclases, dehydratases, heterocycles, polyketides, double hotdog fold, lyase |
Biological source | Sorangium cellulosum |
Total number of polymer chains | 2 |
Total formula weight | 64366.31 |
Authors | Sung, K.H.,Berkhan, G.,Hollmann, T.,Wagner, L.,Hahn, F.,Blankenfeldt, W. (deposition date: 2017-05-18, release date: 2017-11-08, Last modification date: 2024-01-17) |
Primary citation | Sung, K.H.,Berkhan, G.,Hollmann, T.,Wagner, L.,Blankenfeldt, W.,Hahn, F. Insights into the Dual Activity of a Bifunctional Dehydratase-Cyclase Domain. Angew. Chem. Int. Ed. Engl., 57:343-347, 2018 Cited by PubMed: 29084363DOI: 10.1002/anie.201707774 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.174 Å) |
Structure validation
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