5O0Y

TLK2 kinase domain from human

Summary for 5O0Y

Entry DOI	10.2210/pdb5o0y/pdb
Descriptor	Serine/threonine-protein kinase tousled-like 2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (2 entities in total)
Functional Keywords	kinase, atpgs, chromatin remodelling, dna replication, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	67915.76
Authors	Mortuza, G.B.,Montoya, G. (deposition date: 2017-05-17, release date: 2018-05-30, Last modification date: 2024-05-08)
Primary citation	Mortuza, G.B.,Hermida, D.,Pedersen, A.K.,Segura-Bayona, S.,Lopez-Mendez, B.,Redondo, P.,Ruther, P.,Pozdnyakova, I.,Garrote, A.M.,Munoz, I.G.,Villamor-Paya, M.,Jauset, C.,Olsen, J.V.,Stracker, T.H.,Montoya, G. Molecular basis of Tousled-Like Kinase 2 activation. Nat Commun, 9:2535-2535, 2018 Cited by PubMed: 29955062 DOI: 10.1038/s41467-018-04941-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.86 Å)

Structure validation