5O0S

Crystal structure of txGH116 (beta-glucosidase from Thermoanaerobacterium xylolyticum) in complex with unreacted beta Cyclophellitol Cyclosulfate probe ME711

Summary for 5O0S

• Entry DOI: 10.2210/pdb5o0s/pdb
• Related: 5NPF
• Descriptor: Glucosylceramidase, 1,2-ETHANEDIOL, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Thermoanaerobacterium xylanolyticum LX-11
• Total number of polymer chains: 1
• Total formula weight: 91221.52

Authors

Wu, L.,Offen, W.A.,Breen, I.Z.,Davies, G.J. (deposition date: 2017-05-16, release date: 2017-08-09, Last modification date: 2024-01-17)

• Primary citation: Artola, M.,Wu, L.,Ferraz, M.J.,Kuo, C.L.,Raich, L.,Breen, I.Z.,Offen, W.A.,Codee, J.D.C.,van der Marel, G.A.,Rovira, C.,Aerts, J.M.F.G.,Davies, G.J.,Overkleeft, H.S.; 1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor.; ACS Cent Sci, 3:784-793, 2017; PubMed: 28776021; DOI: 10.1021/acscentsci.7b00214

Experimental method

X-RAY DIFFRACTION (1.16 Å)