5NXD

LIM Domain Kinase 2 (LIMK2) In Complex With TH-300

5NXD の概要

• エントリーDOI: 10.2210/pdb5nxd/pdb
• 分子名称: LIM domain kinase 2, 4-[(3-chlorophenyl)sulfamoyl]-~{N}-(phenylmethyl)-~{N}-propyl-benzamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: kinase actin cytoskeleton inhibitor dfg-out, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Isoform LIMK2a: Cytoplasm. Isoform LIMK2b: Cytoplasm: P53671
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70609.47

構造登録者

Mathea, S.,Salah, E.,Hanke, T.,Newman, J.A.,Oerum, S.,Wang, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N.,Knapp, S. (登録日: 2017-05-10, 公開日: 2017-05-24, 最終更新日: 2024-01-17)

• 主引用文献: Mathea, S.,Salah, E.,Hanke, T.,Newman, J.A.,Oerum, S.,Wang, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N.,Knapp, S.; LIM Domain Kinase 2 (LIMK2)In Complex With TH-300; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)