5NRG

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02

Summary for 5NRG

Entry DOI	10.2210/pdb5nrg/pdb
Related	5HKV
Descriptor	23S ribosomal RNA, 50S ribosomal protein L15, 50S ribosomal protein L16, ... (32 entities in total)
Functional Keywords	ribosome, rna, antibiotics, lincosamides
Biological source	Staphylococcus aureus subsp. aureus NCTC 8325 More
Total number of polymer chains	26
Total formula weight	1344440.78
Authors	Yonath, A.,Matzov, D.,Eyal, Z.,Ben Hamou, R.,Zimmerman, E.,Rozenberg, H.,Bashan, A.,Fridman, M. (deposition date: 2017-04-23, release date: 2017-08-09, Last modification date: 2024-01-17)
Primary citation	Matzov, D.,Eyal, Z.,Benhamou, R.I.,Shalev-Benami, M.,Halfon, Y.,Krupkin, M.,Zimmerman, E.,Rozenberg, H.,Bashan, A.,Fridman, M.,Yonath, A. Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus. Nucleic Acids Res., 45:10284-10292, 2017 Cited by PubMed: 28973455 DOI: 10.1093/nar/gkx658 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.442 Å)

Structure validation