5NP3

Abl2 SH3

Summary for 5NP3

• Entry DOI: 10.2210/pdb5np3/pdb
• Descriptor: Abelson tyrosine-protein kinase 2 (2 entities in total)
• Functional Keywords: signaling, tyrosine phosphorylation, sh3 domain, kinase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 27065.93

Authors

Mero, B.,Radnai, L.,Gogl, G.,Leveles, I.,Buday, L. (deposition date: 2017-04-13, release date: 2018-05-16, Last modification date: 2024-01-17)

• Primary citation: Mero, B.,Radnai, L.,Gogl, G.,Toke, O.,Leveles, I.,Koprivanacz, K.,Szeder, B.,Dulk, M.,Kudlik, G.,Vas, V.,Cserkaszky, A.,Sipeki, S.,Nyitray, L.,Vertessy, B.G.,Buday, L.; Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.; J.Biol.Chem., 294:4608-4620, 2019; PubMed: 30659095; DOI: 10.1074/jbc.RA118.004732

Experimental method

X-RAY DIFFRACTION (2 Å)