5NNJ

Dimer structure of Sortilin ectodomain crystal form 3, 4.0 Angstrom

5NNJ の概要

• エントリーDOI: 10.2210/pdb5nnj/pdb
• 分子名称: Sortilin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: transport receptor, vps10 domain, transport protein
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 331033.48

構造登録者

Leloup, N.O.L.,Janssen, B.J.C. (登録日: 2017-04-09, 公開日: 2017-11-29, 最終更新日: 2024-01-17)

• 主引用文献: Leloup, N.,Lossl, P.,Meijer, D.H.,Brennich, M.,Heck, A.J.R.,Thies-Weesie, D.M.E.,Janssen, B.J.C.; Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.; Nat Commun, 8:1708-1708, 2017; PubMed: 29167428; DOI: 10.1038/s41467-017-01485-5

実験手法

X-RAY DIFFRACTION (4 Å)