5NMR

Monomeric mouse Sortilin extracellular domain

5NMR の概要

• エントリーDOI: 10.2210/pdb5nmr/pdb
• 分子名称: Sortilin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: vps10 domain family, sorting receptor, ten-bladed beta propeller, 10cc domain, protein transport
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 82457.19

構造登録者

Leloup, N.O.L.,Loessl, P.,Meijer, D.H.M.,Heck, A.J.R.,Thies-Weesie, D.M.E.,Janssen, B.J.C. (登録日: 2017-04-07, 公開日: 2017-12-06, 最終更新日: 2024-01-17)

• 主引用文献: Leloup, N.,Lossl, P.,Meijer, D.H.,Brennich, M.,Heck, A.J.R.,Thies-Weesie, D.M.E.,Janssen, B.J.C.; Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.; Nat Commun, 8:1708-1708, 2017; PubMed: 29167428; DOI: 10.1038/s41467-017-01485-5

実験手法

X-RAY DIFFRACTION (2.1 Å)