5NLJ

Crystal structure of Zn3-E16V human ubiquitin (hUb) mutant adduct, from a solution 70 mM zinc acetate/20% v/v TFE/1.3 mM E16V hUb

Summary for 5NLJ

• Entry DOI: 10.2210/pdb5nlj/pdb
• Related: 3EHV 4K7S 4K7U 4K7W
• Descriptor: Polyubiquitin-B, ACETATE ION, ZINC ION, ... (7 entities in total)
• Functional Keywords: e16v mutant, ligase, ubiquitination, proteasome degradation, signaling protein
• Biological source: Homo sapiens (Human)
• Cellular location: Ubiquitin: Cytoplasm : P0CG47
• Total number of polymer chains: 3
• Total formula weight: 26851.72

Authors

Fermani, S.,Falini, G. (deposition date: 2017-04-04, release date: 2017-04-26, Last modification date: 2024-01-17)

• Primary citation: Fermani, S.,Calvaresi, M.,Mangini, V.,Falini, G.,Bottoni, A.,Natile, G.,Arnesano, F.; Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium.; Chemistry, 24:4140-4148, 2018; PubMed: 29266436; DOI: 10.1002/chem.201705543

Experimental method

X-RAY DIFFRACTION (1.53 Å)