5NKY

Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain

5NKY の概要

• エントリーDOI: 10.2210/pdb5nky/pdb
• 分子名称: Vitamin D3 receptor A, SRC1, (1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-7~{a}-methyl-1-[(1~{S})-1-[(2~{R},5~{S})-5-(2-oxidanylpropan-2-yl)oxolan-2-yl]ethyl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, ... (4 entities in total)
• 機能のキーワード: gene regulation
• 由来する生物種: Danio rerio (Zebrafish); 詳細
• 細胞内の位置: Nucleus: Q9PTN2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36281.39

構造登録者

Rochel, N.,Belorusova, A.Y. (登録日: 2017-04-03, 公開日: 2017-05-24, 最終更新日: 2024-01-17)

• 主引用文献: Belorusova, A.Y.,Martinez, A.,Gandara, Z.,Gomez, G.,Fall, Y.,Rochel, N.; Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain.; Eur J Med Chem, 134:86-96, 2017; PubMed: 28399453; DOI: 10.1016/j.ejmech.2017.03.081

実験手法

X-RAY DIFFRACTION (2.096 Å)