5NG2

Structure of RIP2K(D146N) with bound Staurosporine

5NG2 の概要

• エントリーDOI: 10.2210/pdb5ng2/pdb
• 分子名称: Receptor-interacting serine/threonine-protein kinase 2, STAUROSPORINE, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: rip2k, kinase, inactive state, staurosporine, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71124.82

構造登録者

Pellegrini, E.,Cusack, S. (登録日: 2017-03-16, 公開日: 2017-06-07, 最終更新日: 2024-01-17)

• 主引用文献: Pellegrini, E.,Signor, L.,Singh, S.,Boeri Erba, E.,Cusack, S.; Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.; PLoS ONE, 12:e0177161-e0177161, 2017; PubMed: 28545134; DOI: 10.1371/journal.pone.0177161

実験手法

X-RAY DIFFRACTION (2.8 Å)