5NF9
Structure of Galectin-3 CRD in complex with compound 2
Summary for 5NF9
Entry DOI | 10.2210/pdb5nf9/pdb |
Related | 5NF7 |
Descriptor | Galectin-3, ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-2-acetamido-6-(hydroxymethyl)-5-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4-oxidanyl-oxan-3-yl]-3-methoxy-benzamide (3 entities in total) |
Functional Keywords | galectin-3 crd, cation-pi interactions, sugar binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P17931 |
Total number of polymer chains | 1 |
Total formula weight | 16975.34 |
Authors | Ronin, C.,Atmanene, C.,Gautier, F.M.,Djedaini Pilard, F.,Teletchea, S.,Ciesielski, F.,Vivat Hannah, V.,Grandjean, C. (deposition date: 2017-03-13, release date: 2017-06-21, Last modification date: 2024-01-17) |
Primary citation | Atmanene, C.,Ronin, C.,Teletchea, S.,Gautier, F.M.,Djedaini-Pilard, F.,Ciesielski, F.,Vivat, V.,Grandjean, C. Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3. Biochem. Biophys. Res. Commun., 489:281-286, 2017 Cited by PubMed: 28554839DOI: 10.1016/j.bbrc.2017.05.150 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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