5NDT

Crystal structure of human Pim-1 kinase in complex with a consensus peptide and fragment like molecule (E)-3-(2-(thiophen-2-yl)vinyl)-3,4-dihydroquinoxalin-2(1H)-one

Summary for 5NDT

• Entry DOI: 10.2210/pdb5ndt/pdb
• Descriptor: Serine/threonine-protein kinase pim-1, Pimtide, GLYCEROL, ... (5 entities in total)
• Functional Keywords: serine threonine kinase, transferase, proto-oncogene, fragment, pim-1, consensus peptide
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 37571.85

Authors

Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2017-03-09, release date: 2018-05-16, Last modification date: 2024-01-17)

• Primary citation: Siefker, C.,Heine, A.,Hardes, K.,Steinmetzer, A.,Klebe, G.; A crystallographic fragment study with human Pim-1 kinase; to be published,

Experimental method

X-RAY DIFFRACTION (1.985 Å)