5NDJ
Crystal structure of aminoglycoside TC007 in complex with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA (soaking)
This is a non-PDB format compatible entry.
Summary for 5NDJ
Entry DOI | 10.2210/pdb5ndj/pdb |
Descriptor | 16S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L24, ... (56 entities in total) |
Functional Keywords | translation, ribosome, 30s, 50s, 70s, trna, mrna, bacteria, rna-protein complex, inhibitor, antibiotic, aminoglycoside |
Biological source | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) More |
Total number of polymer chains | 108 |
Total formula weight | 4529172.80 |
Authors | Prokhorova, I.,Djumagulov, M.,Urzhumtsev, A.,Yusupov, M.,Yusupova, G. (deposition date: 2017-03-08, release date: 2018-05-02, Last modification date: 2024-05-08) |
Primary citation | Prokhorova, I.,Altman, R.B.,Djumagulov, M.,Shrestha, J.P.,Urzhumtsev, A.,Ferguson, A.,Chang, C.T.,Yusupov, M.,Blanchard, S.C.,Yusupova, G. Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114:E10899-E10908, 2017 Cited by PubMed: 29208708DOI: 10.1073/pnas.1715501114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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