5NDE

Crystal structure of metallo-beta-lactamase SPM-1 in space group P4222

Summary for 5NDE

Entry DOI	10.2210/pdb5nde/pdb
Descriptor	Beta-lactamase IMP-1, ZINC ION, SULFATE ION, ... (6 entities in total)
Functional Keywords	lactamase, inhibitor, cyclobutanone, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	2
Total formula weight	57162.44
Authors	Hinchliffe, P.,Spencer, J. (deposition date: 2017-03-08, release date: 2018-01-17, Last modification date: 2024-01-17)
Primary citation	Abboud, M.I.,Kosmopoulou, M.,Krismanich, A.P.,Johnson, J.W.,Hinchliffe, P.,Brem, J.,Claridge, T.D.W.,Spencer, J.,Schofield, C.J.,Dmitrienko, G.I. Cyclobutanone Mimics of Intermediates in Metallo-beta-Lactamase Catalysis. Chemistry, 24:5734-5737, 2018 Cited by PubMed: 29250863 DOI: 10.1002/chem.201705886 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation