5NDB
Crystal structure of metallo-beta-lactamase SPM-1 complexed with cyclobutanone inhibitor
Summary for 5NDB
Entry DOI | 10.2210/pdb5ndb/pdb |
Descriptor | Beta-lactamase IMP-1, ZINC ION, GLYCEROL, ... (9 entities in total) |
Functional Keywords | lactamase, inhibitor, cyclobutanone, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 57883.29 |
Authors | Hinchliffe, P.,Spencer, J. (deposition date: 2017-03-08, release date: 2018-01-17, Last modification date: 2024-01-17) |
Primary citation | Abboud, M.I.,Kosmopoulou, M.,Krismanich, A.P.,Johnson, J.W.,Hinchliffe, P.,Brem, J.,Claridge, T.D.W.,Spencer, J.,Schofield, C.J.,Dmitrienko, G.I. Cyclobutanone Mimics of Intermediates in Metallo-beta-Lactamase Catalysis. Chemistry, 24:5734-5737, 2018 Cited by PubMed: 29250863DOI: 10.1002/chem.201705886 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
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