5N95

Tetragonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus

5N95 の概要

• エントリーDOI: 10.2210/pdb5n95/pdb
• 分子名称: 3D polymerase, TRIPHOSPHATE (3 entities in total)
• 機能のキーワード: 3dpolymerase, rna dependent rna polymerases, 5'-fluoracil, nucleotide analogues, viral protein
• 由来する生物種: Foot-and-mouth disease virus
• 細胞内の位置: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Virion : A4H1Z0
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54382.32

構造登録者

Ferrer-Orta, C.,Verdaguer, N. (登録日: 2017-02-24, 公開日: 2017-05-10, 最終更新日: 2024-01-17)

• 主引用文献: de la Higuera, I.,Ferrer-Orta, C.,de Avila, A.I.,Perales, C.,Sierra, M.,Singh, K.,Sarafianos, S.G.,Dehouck, Y.,Bastolla, U.,Verdaguer, N.,Domingo, E.; Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.; Genome Biol Evol, 9:1212-1228, 2017; PubMed: 28460010; DOI: 10.1093/gbe/evx075

実験手法

X-RAY DIFFRACTION (2.6 Å)