5N7W
Computationally designed functional antibody
Summary for 5N7W
| Entry DOI | 10.2210/pdb5n7w/pdb |
| Descriptor | Antibody Fragment Heavy Chain, Antibody Fragment Light Chain, Interleukin-17A, ... (4 entities in total) |
| Functional Keywords | computationally designed antibody il17, immune system |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 6 |
| Total formula weight | 129625.71 |
| Authors | Hargreaves, D.,Breed, J. (deposition date: 2017-02-21, release date: 2018-11-14, Last modification date: 2018-12-05) |
| Primary citation | Nimrod, G.,Fischman, S.,Austin, M.,Herman, A.,Keyes, F.,Leiderman, O.,Hargreaves, D.,Strajbl, M.,Breed, J.,Klompus, S.,Minton, K.,Spooner, J.,Buchanan, A.,Vaughan, T.J.,Ofran, Y. Computational Design of Epitope-Specific Functional Antibodies. Cell Rep, 25:2121-2131.e5, 2018 Cited by PubMed: 30463010DOI: 10.1016/j.celrep.2018.10.081 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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