5N6O
Wild type human Rac1-GDP
Summary for 5N6O
Entry DOI | 10.2210/pdb5n6o/pdb |
Descriptor | Ras-related C3 botulinum toxin substrate 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | rac, gtpase, gdp, guanine exchange factor, gef, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 40094.15 |
Authors | Cherfils, J.,Ferrandez, Y. (deposition date: 2017-02-15, release date: 2017-12-27, Last modification date: 2024-05-08) |
Primary citation | Ferrandez, Y.,Zhang, W.,Peurois, F.,Akendengue, L.,Blangy, A.,Zeghouf, M.,Cherfils, J. Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule. Sci Rep, 7:14409-14409, 2017 Cited by PubMed: 29089502DOI: 10.1038/s41598-017-13619-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.59 Å) |
Structure validation
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