5N4U
Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and fragment like molekule 5-(2-amino-1,3-thiazol-4-yl)-1,3-dihydrobenzimidazol-2-one
Summary for 5N4U
Entry DOI | 10.2210/pdb5n4u/pdb |
Descriptor | Serine/threonine-protein kinase pim-1, Pimtide, 5-(2-azanyl-1,3-thiazol-4-yl)-1,3-dihydrobenzimidazol-2-one, ... (4 entities in total) |
Functional Keywords | serine threonine kinase, transferase, proto-oncogene, fragment, pim-1, consensus peptide |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 37457.71 |
Authors | Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2017-02-11, release date: 2018-02-28, Last modification date: 2024-01-17) |
Primary citation | Siefker, C.,Heine, A.,Hardes, K.,Steinmetzer, A.,Klebe, G. A crystallographic fragment study with human Pim-1 kinase to be published, |
Experimental method | X-RAY DIFFRACTION (2.202 Å) |
Structure validation
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