5N4C
Prolyl oligopeptidase B from Galerina marginata bound to 35mer hydrolysis and macrocyclization substrate - S577A mutant
Summary for 5N4C
Entry DOI | 10.2210/pdb5n4c/pdb |
Descriptor | Prolyl oligopeptidase, Alpha-amanitin proprotein, GLYCEROL, ... (4 entities in total) |
Functional Keywords | amanitin biosynthesis, prolyl oligopeptidase, macrocyclase, peptidase, beta-propeller, closed form, hydrolase |
Biological source | Galerina marginata More |
Total number of polymer chains | 8 |
Total formula weight | 342935.61 |
Authors | Czekster, C.M.,McMahon, S.A.,Ludewig, H.,Naismith, J.H. (deposition date: 2017-02-10, release date: 2017-11-01, Last modification date: 2024-05-08) |
Primary citation | Czekster, C.M.,Ludewig, H.,McMahon, S.A.,Naismith, J.H. Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates. Nat Commun, 8:1045-1045, 2017 Cited by PubMed: 29051530DOI: 10.1038/s41467-017-00862-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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