5N30
Crystal structure of the V72I mutant of the mouse alpha-Dystroglycan N-terminal region
Summary for 5N30
Entry DOI | 10.2210/pdb5n30/pdb |
Descriptor | Dystroglycan, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (4 entities in total) |
Functional Keywords | dystroglycan cell adhesion laminin binding, cell adhesion |
Biological source | Mus musculus (House Mouse) |
Cellular location | Alpha-dystroglycan: Secreted, extracellular space . Beta-dystroglycan: Cell membrane ; Single-pass type I membrane protein : Q62165 |
Total number of polymer chains | 1 |
Total formula weight | 28604.56 |
Authors | Cassetta, A.,Covaceuszach, S.,Brancaccio, A.,Sciandra, F.,Bozzi, M.,Bigotti, M.G.,Konarev, P.V. (deposition date: 2017-02-08, release date: 2017-11-01, Last modification date: 2024-01-17) |
Primary citation | Covaceuszach, S.,Bozzi, M.,Bigotti, M.G.,Sciandra, F.,Konarev, P.V.,Brancaccio, A.,Cassetta, A. The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of alpha-dystroglycan. PLoS ONE, 12:e0186110-e0186110, 2017 Cited by PubMed: 29036200DOI: 10.1371/journal.pone.0186110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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