5N2W
WT-Parkin and pUB complex
Summary for 5N2W
Entry DOI | 10.2210/pdb5n2w/pdb |
Descriptor | E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ... (6 entities in total) |
Functional Keywords | complex structure of parkin and pub, transferase, ligase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm, cytosol : O60260 Ubiquitin: Cytoplasm : P0CG47 |
Total number of polymer chains | 2 |
Total formula weight | 54949.82 |
Authors | Kumar, A.,Chaugule, V.K.,Johnson, C.,Toth, R.,Sundaramoorthy, R.,Knebel, A.,Walden, H. (deposition date: 2017-02-08, release date: 2017-04-19, Last modification date: 2024-01-17) |
Primary citation | Kumar, A.,Chaugule, V.K.,Condos, T.E.C.,Barber, K.R.,Johnson, C.,Toth, R.,Sundaramoorthy, R.,Knebel, A.,Shaw, G.S.,Walden, H. Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat. Struct. Mol. Biol., 24:475-483, 2017 Cited by PubMed: 28414322DOI: 10.1038/nsmb.3400 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.68 Å) |
Structure validation
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