Summary for 5MZ4
Entry DOI | 10.2210/pdb5mz4/pdb |
Related | 5lkl |
Descriptor | Genome polyprotein,Genome polyprotein (2 entities in total) |
Functional Keywords | flaviviridae, ns3/ns4a, protease/helicase, viral protein |
Biological source | Classical swine fever virus (strain Alfort) (CSFV) More |
Cellular location | E(rns) glycoprotein: Host membrane; Peripheral membrane protein. Envelope glycoprotein E2: Host cell surface . Cysteine protease NS2: Host membrane ; Multi-pass membrane protein : P19712 |
Total number of polymer chains | 2 |
Total formula weight | 167338.66 |
Authors | Tortorici, M.A.,Rey, F.A. (deposition date: 2017-01-30, release date: 2017-02-15, Last modification date: 2024-01-17) |
Primary citation | Dubrau, D.,Tortorici, M.A.,Rey, F.A.,Tautz, N. A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis. PLoS Pathog., 13:e1006134-e1006134, 2017 Cited by PubMed: 28151973DOI: 10.1371/journal.ppat.1006134 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.048 Å) |
Structure validation
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